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IV vs Perineural Dexamethasone for Supraclavicular Block
September 2025
IV vs Perineural Dexamethasone for Supraclavicular Block
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Exploring the Additive or Synergistic Effects of the Systemic and Perineural Routes of Dexamethasone as Adjuncts to Supraclavicular Block: A Randomized Controlled Trial.
Anesthesiology . 2025 Jun 1;142(6):1127-1137.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred four patients with elective wrist/hand surgery under supraclavicular block were randomized to intravenous dexamethasone 10 mg (n=37), combined perineural 5 mg + intravenous 5 mg dexamethasone (n=34), or placebo (n=33). The primary outcome was sensory block duration. Secondary outcomes included motor block duration; rebound pain 2 h after first pain; worst pain at 8, 16, 24, 32, 40, and...
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