Increased mortality with metal-on-metal total hip arthroplasty over long-term follow-up

PLoS One. 2016 Jun 13;11(6):e0156051. doi: 10.1371/journal.pone.0156051. eCollection 2016

A large metal-on-metal total hip prosthesis does not provide additional increases to ROM

Int Orthop. 2011 Dec;35(12):1771-6. Epub 2011 Mar 4

Metal ions and moderate pseudotumor development reduced with large- vs. small-head MoM THA

Bone Joint J. 2018 Aug;100-B(8):1018-1024

Comparison of adverse events between metal-on-metal hip resurfacing prostheses and THA

Clin Orthop Relat Res. 2014 Jul;472(7):2217-30

Large femoral head metal-on-metal THA, follow-up at 2 years

J Orthop. 2015 Jun 10;12(4):228-36

AAOS: Metal ion release substantially increased with metal on metal articulation in THA

TKR: No difference between all-polyethylene and metal-backed tibial implants

J Bone Joint Surg Br. 2006 Dec;88(12):1596-602

36mm metal-on-metal THA increases metal ion & erythrocyte cobalt levels vs 28mm bearing

J Bone Joint Surg Am. 2014 Mar 19;96(6):448-55. doi: 10.2106/JBJS.M.00164.

Systemic cobalt release after metal-on-metal total hip arthroplasty: 5 year follow-up

J Bone Joint Surg Am. 2003 Nov;85-A(11):2168-73

Large modular metal-on-metal bearings in routine primary hip replacement

J Bone Joint Surg Br; 2011; 93(12): 1602-1609

COA: Increased metal ion levels with metal compared to polyethylene inserts in THA

Comparison of revision rate and metal ion release in ceramic-on-metal & metal-on-metal THA

Clin Orthop Relat Res. 2016 Feb;474(2):447-55

THA: 3-fold complication rate with Metal-on-Metal bearings

J Arthroplasty. 2012 Dec;27(10):1844-9. doi: 10.1016/j.arth.2012.05.023. Epub 2012 Jul 6

Surgical treatment of unstable, multi-fragmented radial head fractures

International Orthopedics; 2011; 35; 1071-1076

COA 2015: More revision & metal ions with large head metal-on-metal vs hip resurfacing THA

High risk of elevated metal ion concentrations for patients who undergo metal-on-metal THA

Arch Orthop Trauma Surg. 2011 Nov;131(11):1573-83. doi: 10.1007/s00402-011-1325-2. Epub 2011 Jun 4

Metal-on-metal THA increases HLA DR+CD8+ T-cells & correlates with immunological reactions

Acta Orthop. 2011 Feb;82(1):6-12. Epub 2010 Dec 29

Metal-on-metal arthroplasty produces an increase in body cobalt and nickel concentration

J Arthroplasty. 2009 Sep;24(6):837-45. Epub 2008 Sep 26.

Higher incidence of pseudotumour formation and elevated cobalt levels with MoM vs MoP THA

Bone Joint J. 2015 Nov;97-B(11):1481-7

NZOA 2013: Metal-on-metal and ceramic-on-metal surface bearings in THA