AAOS: Tranexamic acid equally effective when administered topically & intravenously in TKA

IV and/or IA TXA effective in navigated TKA, but combined IV-IA TXA not more effective

J Arthroplasty. 2017 Jan;32(1):37-42

Tanezumab: A future option for pain control in knee osteoarthritis?

N Engl J Med. 2010 Oct 14;363(16):1521-31.

IV Dexamethasone offers postoperative pain reduction in femoral neck fracture fixation

BMC Anesthesiol. 2016 Sep 22;16(1):79

Combination of intravenous and topical TXA improves outcomes following primary TKA

J Arthroplasty. 2014 Dec;29(12):2342-6.

40 vs 8mg dexamethasone dose: similar analgesia reported after shoulder surgery

Acta Anaesthesiol Scand. 2014 Jul;58(6):751-8. doi: 10.1111/aas.12333. Epub 2014 May 13.

Zoledronic acid affects men and women similarly in increasing bone mass after hip fracture

J Am Geriatr Soc. 2011 Nov;59(11):2084-90. doi: 10.1111/j.1532-5415.2011.03666.x. Epub 2011 Oct 21

AAOS 2015: No difference between topical and intravenous tranexamic acid for TKA

Reduced blood loss during early postoperative period after TKA with IV tranexamic acid

Knee. 2006 Mar;13(2):106-10. Epub 2006 Feb 17

Continuous lumbar plexus blockade provides excellent post-operative analgesia for THA

J Bone Joint Surg Am. 2009 Jan;91(1):29-37

No difference between uniform and weighted dosing of TXA for hemostasis after TKA

J Arthroplasty. 2014 Sep;29(9 Suppl):186-8

Intrathecal and intravenous clonidine with bupivacaine in children undergoing surgery

Paediatr Anaesth. 2011 Apr;21(4):399-405. doi: 10.1111/j.1460-9592.2011.03543.x

IV and topical TXA superior to placebo for hematological outcomes after PLIF

World Neurosurg. 2019 Feb;122:e821-e827.

Parecoxib reduces pain and local inflammation factors 3 days after TKA

Eur J Orthop Surg Traumatol. 2014 Apr;24(3):395-401. doi: 10.1007/s00590-013-1203-4. Epub 2013 Mar 13.

TKA: Topical fibrin spray significantly reduces total blood loss

Knee. 2012 Aug;19(4):295-8. Epub 2011 Jul 5

Zoledronic acid given upfront maintains BMD in postmenopausal breast cancer patients

Cancer. 2012 Mar 1;118(5):1192-201. doi: 10.1002/cncr.26313. Epub 2011 Oct 10

Tocilizumab more effective in reducing rheumatoid arthritis symptoms than adalimumab

Lancet. 2013 May 4;381(9877):1541-50. doi: 10.1016/S0140-6736(13)60250-0. Epub 2013 Mar 18

ISAKOS2017: Efficacy of IORA vs. IV vancomycin in revision total knee arthroplasty

Postoperative blood loss reduced with IV TXA in single-bundle ACL reconstruction

Arthroscopy. 2019 Jan;35(1):149-157. doi: 10.1016/j.arthro.2018.07.050

TXA effective in reducing blood loss up to 24 hours after calcaneal fracture surgery

J Foot Ankle Surg. 2015 Nov-Dec;54(6):1106-10.