AAOS: Tranexamic acid equally effective when administered topically & intravenously in TKA
Comparison of IV and topical tranexamic acid in total knee arthroplasty: a prospective randomized study
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85 patients with end stage knee arthritis scheduled to undergo total knee arthroplasty (TKA) were randomized to receive tranexamic acid (TXA) administered either topically or intravenously. The purpose of this study was to compare the efficacy and safety of these two treatment approaches. Results indicated that TXA when topically-applied, resulted in similar haemoglobin values, postoperative drain...
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