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TKA: Interval clamping drain provides greater bleeding control than non-clamping methods
Arch Orthop Trauma Surg. 2012 Jul;132(7):1059-63. doi: 10.1007/s00402-012-1501-z. Epub 2012 Mar 13
No advantage shown for drainage-clamping methods following TKA
J Arthroplasty. 2010 Dec;25(8):1240-5
TKA: Drain-clamping with tranexamic acid decreased drained blood volume/ transfusions
BMC Musculoskelet Disord. 2012 Jul 20;13:124. doi: 10.1186/1471-2474-13-124
Reduced blood loss during TKA with drain clamping and injection of saline with adrenaline
J Bone Joint Surg Br. 2006 Jan;88(1):49-53
Clamping drainage reduces blood loss and transfusions after TKA
Int Orthop. 2009 Oct;33(5):1275-8. Epub 2008 Oct 17.
Four-hour postoperative drain clamping does not reduce blood loss following TKA
Knee Surg Sports Traumatol Arthrosc. 2013 Dec;21(12):2831-6. doi: 10.1007/s00167-012-2253-6. Epub 2012 Oct 23
TKA: Tranexamic acid reduces blood loss without increasing risk of DVT
J Arthroplasty. 2012 Jan;27(1):105-8. Epub 2011 Mar 23
Local Injection of Tranexamic Acid vs Drain Clamping in Total Knee Arthroplasty
BMC Musculoskelet Disord. 2022 01-Feb;():. 10.1186/s12891-022-05058-6
Decreased hemarthrosis and pain with TXA + drain vs drain alone post ACLR
Am J Sports Med. 2015 Nov;43(11):2720-6.
Low- and high-dose TXA effective in reducing blood loss and transfusion needs in TKA
BMC Musculoskelet Disord. 2013 Dec 5;14:340. doi: 10.1186/1471-2474-14-340
Intravenous, intraarticular irrigation, and drain administration of TXA in TKA
J Arthroplasty. 2014 Aug;29(8):1521-4
TKA: Intra-articular tranexamic acid reduces blood loss and knee joint swelling
Int Orthop; 2011; 35(11):1639-1645
TKA: Non-continuous drainage is equally safe, yet more effective than continuous drainage
Int Orthop. 2014 Feb;38(2):361-71. doi: 10.1007/s00264-013-2105-0. Epub 2013 Sep 19.
Greater efficacy of 15mg/kg TXA versus 10mg/kg TXA in total hip arthroplasty
Thromb Res. 2016 May;141:119-23
Combination of intravenous and topical TXA improves outcomes following primary TKA
J Arthroplasty. 2014 Dec;29(12):2342-6.
Topical and intravenous tranexamic acid equally effective in total knee arthroplasty
Knee. 2014 Dec;21(6):987-993
Efficacy of various tranexamic acid administration techniques to reduce blood loss in TKA
Knee Surg Sports Traumatol Arthrosc. 2014 Dec;22(12):3181-90.