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Local Injection of Tranexamic Acid vs Drain Clamping in Total Knee Arthroplasty
March 2022
Local Injection of Tranexamic Acid vs Drain Clamping in Total Knee Arthroplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The effect of local injection of tranexamic acid into peri-articular tissue versus drain clamping in total knee arthroplasty: a randomized controlled trial
BMC Musculoskelet Disord. 2022 Feb 2;23(1):111.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred and twenty patients undergoing total knee arthroplasty were randomized to receive local tranexamic acid injections (n=60) or tranexamic acid through a drain with drain clamping (n=60). The primary outcome measure of interest was calculated total blood loss. Secondary outcomes of interest included drained blood loss, hidden blood loss, D-dimer levels, post-operative knee pain, range of ...
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