Local Injection of Tranexamic Acid vs Drain Clamping in Total Knee Arthroplasty
The effect of local injection of tranexamic acid into peri-articular tissue versus drain clamping in total knee arthroplasty: a randomized controlled trialBMC Musculoskelet Disord. 2022 Feb 2;23(1):111.
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One hundred and twenty patients undergoing total knee arthroplasty were randomized to receive local tranexamic acid injections (n=60) or tranexamic acid through a drain with drain clamping (n=60). The primary outcome measure of interest was calculated total blood loss. Secondary outcomes of interest included drained blood loss, hidden blood loss, D-dimer levels, post-operative knee pain, range of ...
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