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Volume:3 Issue:4 Number:57 ISSN#:2563-5476
Author Verified
RCT
ACE Report #6028
Ace Report Cover Arthroplasty

IV tranexamic acid reduces postoperative autologous blood retransfusion in THA and TKA


How to Cite

OrthoEvidence. IV tranexamic acid reduces postoperative autologous blood retransfusion in THA and TKA. ACE Report. 2014;3(4):57. Available from: https://myorthoevidene.com/AceReport/Report/6028

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Influence of tranexamic acid on postoperative autologous blood retransfusion in primary total hip and knee arthroplasty: a randomized controlled trial

Transfusion. 2014 Jan;54(1):31-41. doi: 10.1111/trf.12224.

Contributing Authors: S Oremus K Sostaric V Trkulja M Haspl

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Synopsis

98 patients undergoing TKA or THA were randomized to receive a restrictive blood transfusion program either with an intraoperative intravenous 1.0 g dose of tranexamic acid (TXA) and a repeated dose 3 hours later or a placebo. Analysis revealed that a lower proportion of TXA patients required reinfusion of postoperatively collected autologous blood, in addition to a reduction in mean total extern...

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