
IV tranexamic acid reduces postoperative autologous blood retransfusion in THA and TKA

IV tranexamic acid reduces postoperative autologous blood retransfusion in THA and TKA
Influence of tranexamic acid on postoperative autologous blood retransfusion in primary total hip and knee arthroplasty: a randomized controlled trial
Transfusion. 2014 Jan;54(1):31-41. doi: 10.1111/trf.12224.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
98 patients undergoing TKA or THA were randomized to receive a restrictive blood transfusion program either with an intraoperative intravenous 1.0 g dose of tranexamic acid (TXA) and a repeated dose 3 hours later or a placebo. Analysis revealed that a lower proportion of TXA patients required reinfusion of postoperatively collected autologous blood, in addition to a reduction in mean total extern...
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