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IV tranexamic acid reduces postoperative autologous blood retransfusion in THA and TKA
April 2014
IV tranexamic acid reduces postoperative autologous blood retransfusion in THA and TKA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Influence of tranexamic acid on postoperative autologous blood retransfusion in primary total hip and knee arthroplasty: a randomized controlled trial
Transfusion. 2014 Jan;54(1):31-41. doi: 10.1111/trf.12224.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
98 patients undergoing TKA or THA were randomized to receive a restrictive blood transfusion program either with an intraoperative intravenous 1.0 g dose of tranexamic acid (TXA) and a repeated dose 3 hours later or a placebo. Analysis revealed that a lower proportion of TXA patients required reinfusion of postoperatively collected autologous blood, in addition to a reduction in mean total extern...
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