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Ace Report Cover

Estrogens decrease joint pain, but do not reduce joint swelling, in post-menopausal women

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Ace Report Cover
September 2013

Estrogens decrease joint pain, but do not reduce joint swelling, in post-menopausal women

Vol: 2| Issue: 8| Number:17| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Estrogen alone and joint symptoms in the Women's Health Initiative randomized trial

Menopause. 2013 Jun;20(6):600-608

Contributing Authors:
RT Chlebowski DJ Cirillo CB Eaton ML Stefanick M Pettinger LD Carbone KC Johnson MS Simon NF Woods J Wactawski-Wende

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Synopsis

10,739 post-menopausal women (50-79 years) who have had a hysterectomy and no prior history of breast cancer were randomized to receive daily oral conjugated equine estrogens (0.625 mg/d) or an equivalent placebo for a mean period of 7.1 years to determine the effectiveness of estrogen alone on joint symptoms. Results at 1 year, including data from all participants, indicated that estrogen signifi...

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