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Estrogens decrease joint pain, but do not reduce joint swelling, in post-menopausal women
September 2013
Estrogens decrease joint pain, but do not reduce joint swelling, in post-menopausal women
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Estrogen alone and joint symptoms in the Women's Health Initiative randomized trial
Menopause. 2013 Jun;20(6):600-608Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
10,739 post-menopausal women (50-79 years) who have had a hysterectomy and no prior history of breast cancer were randomized to receive daily oral conjugated equine estrogens (0.625 mg/d) or an equivalent placebo for a mean period of 7.1 years to determine the effectiveness of estrogen alone on joint symptoms. Results at 1 year, including data from all participants, indicated that estrogen signifi...
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