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Effect of Oral Collagen Supplementation On Knee Osteoarthritis in Adults
March 2025
Effect of Oral Collagen Supplementation On Knee Osteoarthritis in Adults
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Effect of collagen supplementation on knee osteoarthritis: an updated systematic review and meta-analysis of randomised controlled trials.
Clin Exp Rheumatol . 2025 Jan;43(1):126-134.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
This meta-analysis included 11 randomized controlled trials involving 870 patients with knee osteoarthritis, comparing oral collagen supplementation to placebo. Pooled outcomes of interest included pain relief, functional improvement (WOMAC), and safety (adverse events). The analysis showed significant improvements in pain and function favoring collagen. Clinically meaningful changes were observed...
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