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Collagenase Clostridium histolyticum vs Needle Fasciotomy for Primary MCP Dupuytren Contracture
February 2025
Collagenase Clostridium histolyticum vs Needle Fasciotomy for Primary MCP Dupuytren Contracture
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Collagenase Clostridium histolyticum Versus Needle Fasciotomy for Primary Metacarpophalangeal Dupuytren Contracture: Five-Year Results from a Randomized Controlled Trial.
JB JS Open Access . 2024 Nov 20;9(4):e24.00038.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Eighty patients with a single-digit primary MCP joint contracture of ≥30° due to Dupuytren disease were randomized to receive either CCH (n=40) or PNF (n=40). The primary outcome was the reduction in MCP flexion contracture from baseline to 2 years. Secondary outcomes included complications, grip strength, patient-reported pain and hand function scores, treatment satisfaction, recurrence, and retr...
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