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Minimizing Blood Loss Using Tranexamic Acid in Patients Undergoing Spine Surgery

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Ace Report Cover
August 2023

Minimizing Blood Loss Using Tranexamic Acid in Patients Undergoing Spine Surgery

Vol: 303| Issue: 8| Number:27| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Single Dose of Tranexamic Acid Effectively Reduces Blood Loss in Patients Undergoing Spine Surgery: A Prospective Randomized Controlled Trial.

World Neurosurg . 2023 Jul;175:e964-e968.

Contributing Authors:
A Reyes-Sanchez A Domi­nguez-Soto B Zarate-Kalfopulos J Guerra-Garza R Gordillo-Perez C Huffman LM Rosales-Olivarez A Alpizar-Aguirre CL Garci­a-Ramos

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Synopsis

Sixty patients undergoing spine surgery were randomized to receive either tranexamic acid (TXA; n=30) or a placebo (n=30). Outcomes of interest included hemoglobin level, intraoperative blood loss, drainage volume, total blood loss, units of blood transfused, operative time, incidence of adverse events, and length of stay. Intraoperative blood loss was significantly lower in the TXA group. All oth...

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