Celecoxib vs. diclofenac plus omeprazole for OA or RA treatment with lesser GI risk
How to Cite
OrthoEvidence. Celecoxib vs. diclofenac plus omeprazole for OA or RA treatment with lesser GI risk. ACE Report. 2013;2(7):358. Available from: https://myorthoevidene.com/AceReport/Report/133
Celecoxib versus omeprazole and diclofenac in patients with osteoarthritis and rheumatoid arthritis (CONDOR): a randomised trialLancet. 2010 Jul 17;376(9736):173-9. Epub 2010 Jun 16
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4484 cardiovascularly healthy patients with a clinical diagnosis of osteoarthritis or rheumatoid arthritis were randomized to be treated with either selective cox-2 inhibitor NSAID (celecoxib) or a combination of non-selective NSAID (diclofenac) and a proton pump inhibitor (omeprazole) for at least 6 months. After 6 months of treatment observation period, the rate of clinically significant GI even...
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