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Better 6-week result in carpal tunnel syndrome treatment with steroid injection vs. night splinting

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Ace Report Cover
March 2019

Better 6-week result in carpal tunnel syndrome treatment with steroid injection vs. night splinting

Vol: 8| Issue: 3| Number:11| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A

The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial

Lancet. 2018 Oct 20;392(10156):1423-1433. doi: 10.1016/S0140-6736(18)31572-1

Contributing Authors:
EM Hay LS Chesterton DA van der Windt E Roddy KS Dziedzic M Blagojevic-Bucknall C Burton G Davenport SM Jowett HL Myers R Oppong T Rathod-Mistry

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Synopsis

234 patients with carpal tunnel syndrome were randomized to a single injection of 20mg methylprednisolone acetate or 6 weeks of nightly splinting. Patients were assessed primarily for outcomes on the Boston Carpal Tunnel Questionnaire at 6 weeks and 6 months. In addition, cost-utility analysis was performed. Results for the BCTQ Symptom Severity Score and Functional Status Score significantly favo...

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