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RCT
ACE Report #10723
Ace Report Cover Hand & Wrist

Low-dose radiation therapy ineffective versus sham for alleviating symptomatic hand osteoarthritis


Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Lack of beneficial effects of low-dose radiation therapy on hand osteoarthritis symptoms and inflammation: a randomised, blinded, sham-controlled trial

Osteoarthritis Cartilage. 2018 Oct;26(10):1283-1290. doi: 10.1016/j.joca.2018.06.010

Contributing Authors: M Kloppenburg AA den Broeder CH van den Ende MJ Minten MM Leseman-Hoogenboom MC Kortekaas JW Leer PMP Poortmans FHJ van den Hoogen

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Synopsis

56 patients with hand osteoarthritis were randomized to either low dose radiation therapy or sham intervention. Protocols were administered over 6 sessions for the duration of 2 weeks, with follow-up performed at 1, 2, and 3 months after treatment. The primary outcomes of OMERACT-OARSI response rate at 3 months demonstrated no significant difference between the LDRT group and the sham group. In ad...

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