
IORA prophylaxis achieves greater vancomycin tissue concentration vs IV administration in TKA

IORA prophylaxis achieves greater vancomycin tissue concentration vs IV administration in TKA
The AAHKS Clinical Research Award: Intraosseous Regional Prophylaxis Provides Higher Tissue Concentrations in High BMI Patients in Total Knee Arthroplasty: A Randomized Trial
J Arthroplasty. 2018 Jul;33(7S):S13-S18. doi: 10.1016/j.arth.2018.03.013Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
22 patients with a BMI over 35 and scheduled for total knee arthroplasty were randomized to either intraosseous regional administration (IORA) vancomycin 500mg or intravenous vancomycin 15mg/kg. Intraoperative samples of subcutaneous fat and femoral bone were obtained and tested for concentrations of vancomycin. Results demonstrated significantly greater concentrations of vancomycin in the IORA gr...
To view the full content, login to your account,
or start your 30-day FREE Trial today.
FREE TRIAL
LOGIN
Forgot Password?
Explore some of our unlocked ACE Reports below!

Learn about our AI Driven
High Impact Search Feature

The OE High Impact metric uses AI to determine the impact a study will have by considering the content of the article itself. Built using the latest advances of natural language processing techniques. OE High Impact predicts an article’s future number of citations than impact factor alone.
Continue
Join the Conversation
Please Login or Join to leave comments.