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IV and/or IA TXA effective in navigated TKA, but combined IV-IA TXA not more effective
October 2017
IV and/or IA TXA effective in navigated TKA, but combined IV-IA TXA not more effective
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Combined Administration of IV and Topical Tranexamic Acid is Not Superior to Either Individually in Primary Navigated TKA
J Arthroplasty. 2017 Jan;32(1):37-42Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
200 patients scheduled for primary, navigated total knee arthroplasty were randomized to one of four groups: intravenous (IV) tranexamic acid administration, intraarticular (IV) TXA administration, combined IV-IA TXA administration, or administration of placebo saline. Patients were assessed for blood loss variables, included total blood loss, postoperative blood loss, haemoglobin and haematocrit ...
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