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Short (24-hr) versus long (5-day) prophylactic antibiotics following open tibial fracture
May 2017
Short (24-hr) versus long (5-day) prophylactic antibiotics following open tibial fracture
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Unblinded randomized control trial on prophylactic antibiotic use in gustilo II open tibia fractures at Kenyatta National Hospital, Kenya
Injury. 2016 Oct;47(10):2288-2293Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
84 Kenyan patients with an open tibial fracture were randomized to a 24-hour prophylactic antibiotic administration protocol or a 5-day prophylactic antibiotic administration protocol. The purpose of this study was to compare the infection rate after 14 days between these two prophylactic antibiotic administration protocols. Results demonstrated no significant difference in the incidence of infect...
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