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Preop oral TXA demonstrates noninferiority to IV TXA in TKA for hemostasis
January 2017
Preop oral TXA demonstrates noninferiority to IV TXA in TKA for hemostasis
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
The James A. Rand Young Investigator's Award: A Randomized Controlled Trial of Oral and Intravenous Tranexamic Acid in Total Knee Arthroplasty: The Same Efficacy at Lower Cost?
J Arthroplasty. 2016 Sep;31(9 Suppl):26-30Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
78 patients scheduled for total knee arthroplasty were randomized to be administered oral or intravenous tranexamic acid (TXA). The purpose of this study was to determine if oral TXA, which costs less, was noninferior to IV TXA. Outcomes included postoperative hemoglobin drop, total blood loss, postoperative drainage volume, transfusion rate, and the incidence of thromboembolic complications. Equi...
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