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Addition of IA steroid injection to exercise not efficacious for knee OA inflammation
December 2016
Addition of IA steroid injection to exercise not efficacious for knee OA inflammation
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Changes in ultrasound assessed markers of inflammation following intra-articular steroid injection combined with exercise in knee osteoarthritis: exploratory outcome from a randomized trial
Osteoarthritis Cartilage. 2016 May;24(5):814-21Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
100 patients with knee osteoarthritis were randomized to receive physical therapy with either an intra-articular (IA) corticosteroid injection of 1mL methylprednisolone (40mg DepoMedrol, Pfizer) dissolved in 4mL lidocaine (10mg/mL, SAD), or an IA placebo injection of 1mL isotonic saline with 4mL lidocaine (10mg/mL, SAD). The purpose of this study was to determine whether an IA corticosteroid injec...
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