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Tanezumab: A future option for pain control in knee osteoarthritis?

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Ace Report Cover
March 2013

Tanezumab: A future option for pain control in knee osteoarthritis?

Vol: 2| Issue: 2| Number:169| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Tanezumab for the Treatment of Pain from Osteoarthritis of the Knee

N Engl J Med. 2010 Oct 14;363(16):1521-31.

Contributing Authors:
NE Lane TJ Schnitzer CA Birbara M Mokhtarani DL Shelton MD Smith MT Brown

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Synopsis

450 patients (age range 40 to 75) with knee osteoarthritis were randomized to receive either different dosages of the Tanezumab (an inhibitor of nerve growth factor) or a placebo, in order to determine the safety and efficacy of the Tanezumab treatment. The Tanezumab treatment group was observed to have reduced pain and improved function of the arthritic knee joint.

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