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No difference in clinical efficacy between single NASHA and placebo injection for knee OA

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Ace Report Cover
January 2016

No difference in clinical efficacy between single NASHA and placebo injection for knee OA

Vol: 5| Issue: 1| Number:21| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Efficacy and safety of a single intra-articular injection of non-animal stabilized hyaluronic acid (NASHA) in patients with osteoarthritis of the knee

Osteoarthritis Cartilage. 2004 Aug;12(8):642-9.

Contributing Authors:
RD Altman C Akermark AD Beaulieu T Schnitzer

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Synopsis

347 patients with knee osteoarthritis were randomized to receive a single injection of either non-animal stabilized hyaluronic acid (NASHA) or saline placebo. The purpose of this study was to compare the effects of NASHA injection on pain reduction, functional improvement, and incidence of adverse events when compared to placebo. Overall data demonstrated that NASHA did not significantly increase ...

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