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Hyaluronate vs distention vs placebo for Knee OA: no difference in osteoarthritis
January 2016
Hyaluronate vs distention vs placebo for Knee OA: no difference in osteoarthritis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Intra-articular sodium hyaluronate 2 mL versus physiological saline 20 mL versus physiological saline 2 mL for painful knee osteoarthritis: a randomized clinical trial.
. 2008 ;():.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
251 patients with symptomatic knee osteoarthritis, who did not respond to conservative or pharmaceutical treatment, were randomized to receive either hyaluronate, 20 mL saline (distention) or 2 mL saline placebo as an intra-articular injection. The purpose of this study was to compare changes in pain and function of the affected knee between the treatment groups. Results indicated that over a 26 w...
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