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Hyaluronate vs distention vs placebo for Knee OA: no difference in osteoarthritis

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Ace Report Cover
January 2016

Hyaluronate vs distention vs placebo for Knee OA: no difference in osteoarthritis

Vol: 5| Issue: 1| Number:53| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Intra-articular sodium hyaluronate 2 mL versus physiological saline 20 mL versus physiological saline 2 mL for painful knee osteoarthritis: a randomized clinical trial.

. 2008 ;():.

Contributing Authors:
C Lundsgaard N Dufour E Fallentin P Winkel C Gluud

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Synopsis

251 patients with symptomatic knee osteoarthritis, who did not respond to conservative or pharmaceutical treatment, were randomized to receive either hyaluronate, 20 mL saline (distention) or 2 mL saline placebo as an intra-articular injection. The purpose of this study was to compare changes in pain and function of the affected knee between the treatment groups. Results indicated that over a 26 w...

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