Zoledronic acid has no continued benefit beyond 6 years for osteoporosis
Zoledronic acid has no continued benefit beyond 6 years for osteoporosis
The Effect of 6 versus 9 Years of Zoledronic Acid Treatment in Osteoporosis: A Randomized Second Extension to the HORIZON-Pivotal Fracture Trial (PFT)
J Bone Miner Res. 2015 May;30(5):934-44.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred and ninety patients were randomized to receive either continued zolderonic acid (ZOL) treatment or were switched to a placebo after six years of ZOL treatment for osteoporosis. Patients received treatment for an additional 3 years to determine continued efficacy and safety of ZOL. Results found that there was no significant benefit to continued ZOL treatment. Additionally, there was a ...
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