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Combined Topical & IV TXA superior to topical TXA alone for reducing blood loss in TKA

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Ace Report Cover
July 2016

Combined Topical & IV TXA superior to topical TXA alone for reducing blood loss in TKA

Vol: 5| Issue: 7| Number:41| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

The Efficacy of Combined Use of Intraarticular and Intravenous Tranexamic Acid on Reducing Blood Loss and Transfusion Rate in Total Knee Arthroplasty

J Arthroplasty. 2015 May;30(5):776-80

Contributing Authors:
SY Lin CH Chen YC Fu PJ Huang JK Chang HT Huang

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Synopsis

One hundred and twenty patients with a diagnosis of primary osteoarthritis (OA) scheduled for unilateral total knee arthroplasty were randomized to receive either a combination of topical and intravenous administration of tranexamic acid, topical administration alone, or a saline control. Initial hemoglobin levels and postoperative drop, total drain amount, total blood loss, and transfusion rate w...

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