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Salmon calcitonin appears ineffective in the management of knee OA treatment in 2 RCTs

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Ace Report Cover
February 2016

Salmon calcitonin appears ineffective in the management of knee OA treatment in 2 RCTs

Vol: 5| Issue: 2| Number:31| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Treatment of symptomatic knee osteoarthritis with oral salmon calcitonin: results from two phase 3 trials

Osteoarthritis Cartilage. 2015 Apr;23(4):532-43.

Contributing Authors:
MA Karsdal I Byrjalsen P Alexandersen A Bihlet JR Andersen BJ Riis AC Bay-Jensen C Christiansen CSMC021C2301/2 investigators

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Synopsis

Two randomized control trials, with a combined 2206 patients, studied the effects of salmon calcitonin (sCT) in patients with symptomatic knee osteoarthritis. Changes in joint space width, pain, function, and safety were evaluated over a 24 month period after treatment began. The results of these trials indicated that salmon calcitonin did not have an effect on joint space width in comparison to p...

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