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AAOS 2015: Autologous chondrocyte implantation vs standard repair of chondral knee defects

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Ace Report Cover
April 2015

AAOS 2015: Autologous chondrocyte implantation vs standard repair of chondral knee defects

Vol: 4| Issue: 4| Number:14| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

A Multi-Center Prospective Randomized Clinical Trial of Autologous Chondrocyte Implantation

Contributing Authors:
JB Richardson J Kuiper J Wales HR Simpson D Marsh N Rushton L Middleton P Harrison R Gray B Ashton

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CONFERENCE ACE REPORTS

This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.

Synopsis

390 patients with chondral knee defects and previously failed surgery were randomized to undergo either autologous chondrocyte implantation (ACI) or an alternative standard repair procedure (ie. microfracture, autologous matrix-induced chrondrogenesis, mosaicplasty, debridement), with the choice of standard treatment left to the patient and surgeon. The purpose of this study was to determine if AC...

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