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Melatonin does not reduce the incidence of delirium among elderly hip fracture patients
January 2015
Melatonin does not reduce the incidence of delirium among elderly hip fracture patients
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Effect of melatonin on incidence of delirium among patients with hip fracture: a multicentre, double-blind randomized controlled trial
CMAJ. 2014 Oct 7;186(14):E547-56.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
452 elderly patients undergoing emergent surgical treatment of hip fracture were randomized to receive melatonin or placebo for a duration of five days after admission. The purpose of this trial was to determine the short-term effects of melatonin on the incidence, duration, and severity of delirium commonly seen in this patient population. Perioperative melatonin supplementation did not reduce th...
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