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Zoledronic acid: best overall bisphosphonate treatment for osteoporosis fractures

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Ace Report Cover
March 2014

Zoledronic acid: best overall bisphosphonate treatment for osteoporosis fractures

Vol: 3| Issue: 3| Number:78| ISSN#: 2564-2537
Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A

The efficacy of bisphosphonates in the prevention of vertebral, hip, and nonvertebral-nonhip fractures in osteoporosis: a network meta-analysis

Semin Arthritis Rheum. 2011 Feb;40(4):275-84.e1-2.

Contributing Authors:
JP Jansen GJ Bergman J Huels M Olson

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Synopsis

8 randomized placebo controlled trials (including over 20,000 patients) that investigated the effects of different bisphosphonate treatments for osteogenesis in postmenopausal women were evaluated with the aim of determining a superior treatment. A network meta-analysis using the Bayesian approach was conducted to analyze the indirect comparisons provided in the study and found that zoledronic aci...

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