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Knee OA treated with chondroitin sulfate: cartilage volume is not associated with symptoms

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Ace Report Cover
August 2013

Knee OA treated with chondroitin sulfate: cartilage volume is not associated with symptoms

Vol: 2| Issue: 7| Number:321| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Effect of 12 months treatment with chondroitin sulfate on cartilage volume in knee osteoarthritis patients: a randomized, double-blind, placebo-controlled pilot study using MRI

Clin Rheumatol. 2012 Sep;31(9):1347-57. doi: 10.1007/s10067-012-2022-4. Epub 2012 Jun 23

Contributing Authors:
JJ Railhac M Zaim AS Saurel J Vial B Fournie

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Synopsis

48 patients with knee osteoarthritis were randomized to receive treatment with Structum (chondroitin sulfate) or a placebo. Over 48 weeks, the Structum group demonstrated an increase in total cartilage volume, whereas the control group demonstrated a decrease. However, this difference was not statistically significant. At 4 weeks, scores for pain, while in motion, were significantly lower in the S...

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