
Zoledronic acid in the prevention and treatment of glucocorticoid-induced osteoporosis

Zoledronic acid in the prevention and treatment of glucocorticoid-induced osteoporosis
Zoledronic acid and risedronate in the prevention and treatment of glucocorticoid-induced osteoporosis (HORIZON): a multicentre, double-blind, double-dummy, randomised controlled trial
Lancet. 2009 Apr 11;373(9671):1253-63Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
833 patients, undergoing treatment with glucocorticoids for 12 months, were randomized to receive zoledronic acid or risedronate in this double blind, double dummy trial. This study assessed the non-inferiority of one injection of zoledronic acid for the prevention and treatment of glucocorticoid induced osteoporosis compared to the daily oral risedronate dosage. Following the one year treatment p...
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