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Effect of Ciprofol on Postoperative Delirium in Elderly Patients Undergoing Hip Surgery

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Ace Report Cover
November 2025

Effect of Ciprofol on Postoperative Delirium in Elderly Patients Undergoing Hip Surgery

Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Effect of Ciprofol on Postoperative Delirium in Elderly Patients Undergoing Hip Surgery: A Randomized Controlled Trial.

Drug Des Devel Ther . 2025 Jul 19:19:6207-6218.

Contributing Authors:
Z Chen YY Liu Q Hu JS Wang RY Cao ST Yu F Lu ML Zhong WD Liang L Wang

Synopsis

One hundred fourteen elderly patients undergoing elective hip joint surgery were randomized to receive ciprofol-based anaesthesia (0.3 mg/kg induction; n=57) or propofol-based anaesthesia (1.5 mg/kg induction; n=57). The primary outcome of interest was the incidence of postoperative delirium (POD) within the first 3 postoperative days, assessed with the 3D-CAM on postoperative days 1 and 3. Second...

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