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Betamethasone Improves Early Pain and Function After Total Knee Arthroplasty
November 2025
Betamethasone Improves Early Pain and Function After Total Knee Arthroplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Comparison of analgesic effects between betamethasone and dexamethasone in total knee arthroplasty: a prospective randomized controlled trial.
Front Med (Lausanne) . 2025 Jul 9:12:1575417.Synopsis
One hundred twenty patients with knee osteoarthritis scheduled for unilateral primary TKA were randomized to receive: (1) ropivacaine-only cocktail (control; n = 40), (2) ropivacaine + dexamethasone 10 mg (n = 40), or (3) ropivacaine + betamethasone 10.52 mg (n = 40). The primary outcome was postoperative VAS pain; secondary outcomes included knee ROM, straight leg raise (SLR), inflammatory marker...
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