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Effect Of High-Dose Dexamethasone On Morphine Use After Periacetabular Osteotomy For Hip Dysplasia

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Ace Report Cover
September 2025

Effect Of High-Dose Dexamethasone On Morphine Use After Periacetabular Osteotomy For Hip Dysplasia

Vol: 307| Issue: 9| Number:3| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Effect of high-dose dexamethasone on morphine use after periacetabular osteotomy for hip dysplasia: a randomized double-blind placebo-controlled single center trial.

Acta Orthop . 2025 Jun 1:96:413-420.

Contributing Authors:
V Lindberg-Larsen M Lindberg-Larsen O Ovesen ST Zwisler P Lindholm S Hebsgaard R Christensen S Overgaard

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Synopsis

Ninety patients with symptomatic hip dysplasia undergoing periacetabular osteotomy were randomized to receive either a single dose of dexamethasone 24 mg preoperatively followed by placebo (n=30), two doses of dexamethasone 24 mg (preoperative and 24 hours postoperative) (n=30), or placebo at both time points (n=30). The primary outcome was cumulative morphine consumption within 48 hours after sur...

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