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Intra-Operative Methylprednisolone in Cervical Myelopathy Surgery
September 2025
Intra-Operative Methylprednisolone in Cervical Myelopathy Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Does Intra-Operative Methylprednisolone Improve Outcomes of Surgery for Degenerative Cervical Myelopathy? - A Prospective Randomized Study.
Global Spine J . 2025 Jun;15(5):2687-2698.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Sixty-five patients with degenerative cervical myelopathy (DCM) were randomized to receive intra-operative methylprednisolone 1 g at the start of decompression (n = 33) or normal saline (n = 32). The primary outcomes were neurological function (mJOA score, Nurick grade) and spinal cord MRI signal (Chen grading). Secondary outcomes included mJOA and Nurick recovery rates, mJOA domain scores (upper ...
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