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Intravenous Versus Oral Acetaminophen For Pain & Quality Of Recovery After Ambulatory Spine Surgery
July 2025
Intravenous Versus Oral Acetaminophen For Pain & Quality Of Recovery After Ambulatory Spine Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Intravenous versus oral acetaminophen for pain and quality of recovery after ambulatory spine surgery: a randomized controlled trial.
Reg Anesth Pain Med . 2025 Jun 10;50(6):483-488.Synopsis
Eighty-two patients undergoing ambulatory lumbar spine surgery were randomized to receive either 1000 mg intravenous acetaminophen (n=42) or 1000 mg oral acetaminophen (n=40). The primary outcome of interest was 24-hour opioid consumption in intravenous morphine milligram equivalents (MMEs). Secondary outcomes included postoperative pain ratings, PACU opioid use, Quality of Recovery (QoR-15) score...
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