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Tranexamic Acid and Heterotopic Ossification After Elbow Fracture–Dislocation Surgery

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Ace Report Cover
September 2025

Tranexamic Acid and Heterotopic Ossification After Elbow Fracture–Dislocation Surgery

Vol: 307| Issue: 9| Number:53| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Tranexamic Acid and Heterotopic Ossification Formation Following Elbow Surgery: A Prospective Randomized Controlled Trial.

J Orthop Trauma . 2025 May 1;39(5):261-268.

Contributing Authors:
E Avisar A Essa R Paul E Kachko O Rabau R Mattan J Persitz

Synopsis

Forty-seven patients with acute traumatic elbow fracture–dislocations were randomized to receive intraoperative TXA (1 g before incision and 1 g at closure; n=23) or no TXA (n=24). The primary outcome of interest was heterotopic ossification (HO) occurrence on serial radiographs. Secondary outcomes included clinically relevant HO (Hastings & Graham grades 2–3), reoperation for symptomatic HO, time...

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