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Effects Of High Impact Exercise On Systemic Cytokines In Women With Mild Knee Osteoarthritis

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Ace Report Cover
July 2025

Effects Of High Impact Exercise On Systemic Cytokines In Women With Mild Knee Osteoarthritis

Vol: 307| Issue: 7| Number:11| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Effects of high impact exercise on systemic cytokines in women with mild knee osteoarthritis: A 12-month RCT.

Osteoarthr Cartil Open . 2025 Apr 11;7(2):100609.

Contributing Authors:
VM Konola J Multanen JK Ihalainen JE Hintikka T Jämsä H Kautiainen MT Nieminen S Pekkala M Valtonen A Heinonen

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Synopsis

Seventy-three postmenopausal women with mild knee osteoarthritis were randomized to receive either a high-impact aerobic/step aerobics training program (n=35) or continue their usual activities as a non-training reference group (n=38). The primary outcome of interest was the change in systemic cytokine levels. Secondary outcomes included associations between cytokines and cartilage quality (MRI T2...

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