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Biphasic Scaffold With Autologous Cartilage Outperforms Marrow Stimulation for Knee Lesions

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Ace Report Cover
June 2025

Biphasic Scaffold With Autologous Cartilage Outperforms Marrow Stimulation for Knee Lesions

Vol: 307| Issue: 6| Number:24| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Biphasic Scaffold Loaded With Autologous Cartilage Yields Better Clinical Outcome and Magnetic Resonance Imaging Filling Compared With Marrow Stimulation for Focal Osteochondral Lesions in the Knee.

Arthroscopy . 2025 Mar;41(3):688-699.

Contributing Authors:
CP Chen PW Weng KT Lee LY Chiang WJ Liao L Shaw

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Synopsis

Fifty-four patients with focal osteochondral knee lesions were randomized to receive either a biphasic scaffold loaded with autologous cartilage (n=27) or marrow stimulation (n=27). The primary outcome was the International Knee Documentation Committee (IKDC) subjective score at 2 years. Secondary outcomes included the Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales and MRI-based car...

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