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Efficacy and Safety Of Loxoprofen Sodium Cataplasms In The Treatment Of Osteoarthritis

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Ace Report Cover
May 2025

Efficacy and Safety Of Loxoprofen Sodium Cataplasms In The Treatment Of Osteoarthritis

Vol: 307| Issue: 5| Number:3| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Efficacy and safety of loxoprofen sodium cataplasms in the treatment of osteoarthritis: A randomized, multicenter study.

Biomed Rep . 2025 Feb 4;22(4):57.

Contributing Authors:
Y Lei Z Liu X Jin G Gao S Luo X Gao Q Liu P Yang R Tian

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Synopsis

Two hundred ninety-six patients with osteoarthritis were randomized to receive either loxoprofen sodium cataplasm (LSC) once daily (n=192) or flurbiprofen cataplasm (FPC) twice daily (n=104) for 2 weeks. The primary outcome was treatment effectiveness based on Visual Analog Scale (VAS), WOMAC global score, and Lysholm score. Secondary outcomes included changes in VAS, WOMAC subdomains (pain, stiff...

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