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Nitrous Oxide Analgesia For Rehabilitation After Anterior Cruciate Ligament Reconstruction

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Ace Report Cover
May 2025

Nitrous Oxide Analgesia For Rehabilitation After Anterior Cruciate Ligament Reconstruction

Vol: 307| Issue: 5| Number:8| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Nitrous oxide analgesia for rehabilitation after anterior cruciate ligament reconstruction: A randomized controlled trial.

Ann Phys Rehabil Med. 2025 Mar;68(2):101897.

Contributing Authors:
Z Wang L Zhou F Wang X Jiang W Wang X Qiu Y Xing C Fu P Zhong L Tang

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Synopsis

One hundred twenty patients undergoing rehabilitation after ACL reconstruction who reported acute pain were randomized to receive either 65% nitrous oxide (n = 60) or 100% oxygen (n = 60). The primary outcome of interest was pain score measured during rehabilitation training. Secondary outcomes included sedation level, range of motion, vital signs, satisfaction of participants and physicians, acce...

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