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Efficacy and Safety of Tranexamic Acid in Reducing Hidden Blood Loss During Kyphoplasty
April 2025
Efficacy and Safety of Tranexamic Acid in Reducing Hidden Blood Loss During Kyphoplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy and Safety of Tranexamic Acid on Hidden Blood Loss in Osteoporotic Vertebral Compression Fractures Patients Treated with Percutaneous Kyphoplasty: A Prospective Randomized Controlled Trial.
Ther Clin Risk Manag . 2024 Dec 25:20:907-917.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred forty-six patients with osteoporotic vertebral compression fractures undergoing percutaneous kyphoplasty were randomized to receive intravenous tranexamic acid (1g, n=75) or placebo (n=71). The primary outcome was hidden blood loss (HBL) on postoperative days 1 and 3. Secondary outcomes included hemoglobin and hematocrit changes, VAS pain scores, and postoperative complications. Outcom...
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