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Efficacy of preoperative prophylactic betamethasone on postoperative TKA nausea and vomit
April 2025
Efficacy of preoperative prophylactic betamethasone on postoperative TKA nausea and vomit
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy of preoperative prophylactic application of betamethasone on postoperative nausea and vomiting in patients undergoing total knee arthroplasty: a prospective randomized controlled trial.
Front Med (Lausanne). 2024 Dec 17;11:1487818.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred twenty-four patients with end-stage knee osteoarthritis undergoing primary unilateral total knee arthroplasty were randomized to receive either intravenous betamethasone sodium phosphate (10.52 mg; n=62) or normal saline placebo (n=62) 10 minutes before anesthesia induction. The primary outcome was severity of nausea, frequency of vomiting, and use of antiemetic medication within 48 ho...
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