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Analgesic Efficacy of Methylene Blue-Enhanced Cocktail in Total Knee Arthroplasty
June 2025
Analgesic Efficacy of Methylene Blue-Enhanced Cocktail in Total Knee Arthroplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Analgesic efficacy and safety of methylene blue combined with cocktail for periarticular infiltration following total knee arthroplasty: a prospective, randomized, controlled study.
Perioper Med (Lond). 2025 Jan 20;14(1):9.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Seventy patients with knee osteoarthritis undergoing total knee arthroplasty were randomized to receive either a periarticular infiltration of methylene blue combined cocktail (n=35) or a conventional cocktail alone (n=35). The primary outcome of interest was postoperative pain scores assessed by the Numeric Rating Scale (NRS). Secondary outcomes of interest included postoperative sufentanil consu...
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