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Probiotics Alleviate Disease Severity and Improve Balance in Osteoarthritis Patients

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Ace Report Cover
March 2025

Probiotics Alleviate Disease Severity and Improve Balance in Osteoarthritis Patients

Vol: 307| Issue: 3| Number:41| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Probiotics' supplementation alleviates disease severity and improves postural balance by repairing intestinal leak in patients suffering from osteoarthritis: a double-blinded clinical trial.

Br J Nutr. 2024 Dec 28;132(12):1602-1610.

Contributing Authors:
A Karim HA Khan MS Iqbal F Ahmad R Qaisar

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Synopsis

One hundred forty-seven patients with knee osteoarthritis (OA) were randomized to receive either a daily multistrain probiotic (Vivomix 112 billion) (n=72) or a placebo (n=75) for 12 weeks. The primary outcome was postural balance. Secondary outcomes included pain intensity (VAS), disease severity (WOMAC index), handgrip strength (HGS), gait speed, and plasma biomarkers of intestinal permeability ...

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