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Leukocyte-Rich vs. Leukocyte-Poor PRP Injections for Knee Osteoarthritis
February 2025
Leukocyte-Rich vs. Leukocyte-Poor PRP Injections for Knee Osteoarthritis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Leukocytes Do Not Influence the Safety and Efficacy of Platelet-Rich Plasma Injections for the Treatment of Knee Osteoarthritis: A Double-Blind Randomized Controlled Trial.
Am J Sports Med. 2024 Nov;52(13):3212-3222.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
One hundred thirty-two patients with Kellgren-Lawrence grade 1-3 knee osteoarthritis were randomized to receive three weekly intra-articular injections of either LR-PRP (n=66) or LP-PRP (n=66). The primary outcome was the change in the International Knee Documentation Committee (IKDC) subjective score at 12 months. Secondary outcomes included pain, function, and quality of life assessed through va...
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