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Magnesium and Bicarbonate Local Infiltration Analgesia for Pain Control After UKA

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Ace Report Cover
September 2025

Magnesium and Bicarbonate Local Infiltration Analgesia for Pain Control After UKA

Vol: 307| Issue: 9| Number:24| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Magnesium sulphate and sodium bicarbonate as additives for periarticular local infiltration analgesia improve pain management after unicompartmental knee arthroplasty: a prospective, double-blind, randomized controlled trial.

J Orthop Surg Res . 2024 Nov 18;19(1):764.

Contributing Authors:
Y Zhu S Shen L Cui L Wu B Zhang

Synopsis

Sixty-one patients with medial compartment osteoarthritis undergoing UKA were randomized to receive a modified local infiltration analgesia (LIA) (n=30) or a conventional LIA (n=31). The primary outcomes were postoperative pain (VAS at rest/motion) and PCIA consumption. Secondary outcomes included time to first rescue analgesia (PCIA), knee range of motion (ROM), daily ambulation distance, time t...

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