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Topical Glyceryl Trinitrate (GTN) and Eccentric Exercises for Mid-Portion Achilles Tendinopathy
January 2025
Topical Glyceryl Trinitrate (GTN) and Eccentric Exercises for Mid-Portion Achilles Tendinopathy
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Topical glyceryl trinitrate (GTN) and eccentric exercises in the treatment of mid-portion achilles tendinopathy (the NEAT trial): a randomised double-blind placebo-controlled trial.
Br J Sports Med . 2024 Sep 9;58(18):1035-1043.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Seventy-six patients with chronic mid-portion Achilles tendinopathy were randomized to receive either 24 weeks of daily GTN ointment (n=37) or placebo ointment (n=39), both combined with a 12-week eccentric exercise program. The primary outcome was improvement in the Victorian Institute of Sports Assessment–Achilles (VISA-A) scores at 24 weeks. Secondary outcomes included pain severity, physical f...
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