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Effects of Hyaluronic Acid, Mesenchymal Stem Cells, and Growth Hormones in Knee Osteoarthritis
January 2025
Effects of Hyaluronic Acid, Mesenchymal Stem Cells, and Growth Hormones in Knee Osteoarthritis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Evaluating Synergistic Effects of Hyaluronic Acid, Human Umbilical Cord-Derived Mesenchymal Stem Cells, and Growth Hormones in Knee Osteoarthritis: A Multi-Arm Randomized Trial.
Biomedicines . 2024 Oct 14;12(10):2332.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Fifty-one knees from 28 patients with Kellgren–Lawrence Grade I-II knee osteoarthritis were randomized to receive one of four treatments: HA alone (n=13), HA with hUC-MSCs (n=12), HA with somatotropin (n=12), or a combination of all three (n=14). The primary outcomes assessed were changes in VAS, WOMAC, and IKDC scores, with secondary outcomes including cartilage regeneration evaluated using MRI T...
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